It has its moments, just like any other sport bike. The Hyper is fairly sensitive to proper suspension set up, so play around with it until you get it where you like it. I certainly wouldn't call it "really twitchy".
- daily commuter in San Francisco - feasible?
Sure, why not?
- i am 6'4" 210 I really liked the that the bike was taller - is comfortable for all of you?
I'm 6' 0", 195, and the bike has plenty of room. You might possibly want to look into some bar risers, but otherwise, you should fit fine. Honestly, at 6' 4", you're going to be big on any sport bike, but whatcha gonna do. Michael Jordan rides Ducatis...
- if i have been off a bike for 5 years - is it to much bike for me?
With 10 years previous experience, you should be fine. Just take it slow for a while and get the cobwebs off. Some people even get a little rusty after the so-called "winter off-season", whatever that is.

Maybe consider taking a refresher MSF course...
Absolutely. If you split lanes a lot, you might want to ditch the stock mirrors and get some optional types. Otherwise, it's an awesome city bike. Torquey, nimble, good visibility all around you. What else could you want?