I haven't ridden the Sport model, but I own a PS 1000LE and the rider position on that one I guess you can say is even more "sporty".
The first couple of tours this spring gave me some problem with my wrists and neck, but from about the third trip these problems just disappeared.
I've done quite a few longer trips (250 mi +) with just fuel filling stops and there haven't been any problems. I really like the rider position because it gives you a very good feeling of what's happening in the front end of the bike, a thing I consider being of a major interest for me while riding

Riding on freeways I expect you to use 6'th gear and then you must up to at least 4000 rpm to make the engine spin. At that speed the wind will unload your wrists so there should not be a problem with that.
Then my wife has a S2R and when I ride it I get this smile on my face as well. But, from getting used to the rider position on the PS I wouldn't trade it for anything that I presently know of.
Try both bikes and keep in mind that if the Sport seems to have too low steering bars, you will very soon get used to it.
Good luck